中医杂志

动脉粥样硬化(AS)斑块是导致血管狭窄的病理基础。基于影像学及病理学发现,认为AS斑块具有与癥瘕相似的形态,而AS斑块脂质沉积、炎症浸润、细胞增殖等病理机制与中医学癥瘕形成的过程基本相似。据此提出AS斑块可称之为"血脉癥瘕",其基本病机可概括为痰凝血瘀、毒伤血脉、血脉失和,治疗可采用散结化斑、解毒稳斑、荣脉抑斑等法。临证根据AS不同的病理阶段进行病证结合治疗,可获较好效果。

Atherosclerosis( AS) plaque is the pathological basis of vascular stenosis. Based on the findings of imaging and pathology,it is believed that AS plaque has similar morphology to the plaque,while the pathological mechanisms of AS plaque such as lipid deposition,inflammatory infiltration,cell proliferation are basically similar to the process of the formation of traditional Chinese medicine( TCM) plaque. According to this,AS plaque can be called "blood meridian mass". Its basic pathogenesis can be summarized as coagulated phlegm and blood stasis,toxin injury of blood vessel,disharmony of blood and meridian,and the treatment can be used by removing stasis and plaque,detoxification and stabilization of plaque,flourishing meridians and inhibiting plaque and so on. According to the different pathological stages of AS,the combination of disease and syndrome can achieve better results.