| 766 | 0 | 143 |
| 下载次数 | 被引频次 | 阅读次数 |
系统梳理伏邪理论的历史源流,认为伏邪的概念界定包括狭义与广义两个层面,狭义特指伏气温病,广义则包括潜伏于体内而不即发的所有邪气,如瘀滞、肿瘤、结石等。伏邪致病具有隐匿性、潜伏性、动态性与复合性特征,不仅表现为潜伏期长,而且随体质、环境变化而不断转化,还常与瘀、痰、火交织形成伏毒而具有复杂的病机。深刻理解中医伏邪理论有助于对自身免疫疾病、肿瘤、传染病等多发疾病的临床诊疗,彰显了伏邪理论的重要价值。重新审视中医伏邪理论,既能为现代临床提供独特的病因学新视角,又可为疾病预防、治疗与康复乃至慢病管理等提供理论支撑。
Abstract:This paper systematically reviews the historical origins and development of the theory of latent pathogen in traditional Chinese medicine(TCM) and proposes that the conceptual definition of latent pathogen encompasses both a narrow and a broad sense. In the narrow sense, it specifically refers to latent qi-induced warm diseases; in the broad sense, it includes all pathogenic factors that remain latent within the body without immediate manifestation, such as blood stasis, tumors, and calculi. The pathogenic characteristics of latent pathogen are marked by concealment, latency, dynamic transformation, and complexity. It is not only characterized by a prolonged incubation period, but also by continuous transformation in response to changes in individual constitution and environmental conditions. Moreover, it often intertwines with blood stasis, phlegm, and fire to form latent toxin, resulting in highly complex pathogenesis. A profound understanding of the TCM theory of latent pathogen is of great significance for the clinical diagnosis and treatment of prevalent diseases such as autoimmune disorders, tumors, and infectious diseases, highlighting the important clinical value of this theory. Re-examining the theory of latent pathogen in TCM not only provides a unique new etiological perspective for modern clinical practice, but also offers theoretical support for disease prevention, treatment, rehabilitation, and even chronic disease management.
[1]赵明芬,安冬青,汪建萍.试论伏邪理论的源流及发展[J].中医杂志,2016, 57(3):189-192.
[2]李经纬,张志斌,余瀛鳌,等.中医大辞典[M]. 2版.北京:人民卫生出版社,1995:535.
[3]郭榕榕,牛阳.《重订广温热论》温热病复证疗法初探[J].光明中医,2020, 35(20):3172-3174.
[4]肖乔,沈影,韩凤娟.伏邪理论与BRCA1/2基因突变:一个中西医结合视角下的卵巢癌发病机制探析[J].天津中医药大学学报,2019, 38(5):427-429.
[5]王新苗,朱潇雨,李杰.基于伏邪理论探析休眠癌细胞的形成、激活、消亡机制及中医干预策略[J].中医杂志,2025,66(12):1217-1221,1256.
[6]王海宏,宋玉,贺凡,等.基于伏邪理论探讨循环肿瘤细胞与结直肠癌复发转移的相关性[J].中医杂志,2024,65(19):1983-1987.
[7]田建辉,罗斌.肺癌“正虚伏毒”病机的生物学基础(二):基于隐匿性肿瘤细胞之肺癌“伏毒”病机探要[J].上海中医药杂志,2018, 52(2):6-10.
[8]秦松林,李卫勇,沈贤发,等.从临床到基础探讨以伏邪论治紫癜性肾炎[J].山东中医杂志,2020, 39(12):1282-1286.
[9]王玉光,齐文升,马家驹,等.新型冠状病毒肺炎中医临床特征与辨证治疗初探[J].中医杂志,2020,61(4):281-285.
[10]张磊,王涓涓,娄志杰,等.从伏邪温病的机制理论探讨中医药治疗新型冠状病毒肺炎的特点[J].天津中医药,2020, 37(9):990-993.
[11]赵晨希,卢红蓉.从伏邪理论探讨新型冠状病毒肺炎的发病特点[J].北京中医药大学学报,2023, 46(1):25-31.
[12]陈玉,肖海娟,王惠玲,等.基于伏邪理论探讨恶性肿瘤发病机制[J].陕西中医,2022, 43(12):1760-1762, 1767.
[13]郭天灏,李柳,程海波.中医肿瘤病机研究述评[J].中国中医基础医学杂志,2024, 30(8):1415-1418.
[14]赵慧颖,梁艳霞,李广森,等.从“阳气亏虚、伏邪传脑”辨治肺癌脑转移[J].中医杂志,2025,66(9):968-972.
[15]王书杰,韦艾凌.肝癌“湿热伏邪”:“癌毒”发病机制及疗法探讨[J].中国中西医结合杂志,2013, 33(2):266-269.
[16]刘东武,李睿,姜兆荣,等.伏邪致病理论在风湿病领域的应用探索[J].中华中医药学刊,2018, 36(5):1078-1080.
[17]刘维,卡玉秀,陈婌娟.难治性类风湿关节炎正虚毒蕴病机论[J].中医杂志,2024,65(22):2368-2372.
[18]窦雨鑫,刘阳,颜梓薇,等.基于“伏邪”理论论治高尿酸血症[J].实用中医内科杂志,2025, 39(5):55-58.
[19]王先敏,赵明芬.从伏邪论治高尿酸血症的理论探讨[J].时珍国医国药,2011, 22(7):1720-1721.
[20]李洪涛,黄雅琪,姚露露,等.从“脑络伏邪”探析针刺辨治中风后吞咽障碍思路[J].中医杂志,2025,66(9):901-905.
[21]柯婷.伏邪内伤学说在中医脑病学中的应用浅析[J].四川中医,2014, 32(2):50-52.
[22]赖胜蓝,钱军,李可帅,等.基于“正虚伏毒”理论探讨乳腺癌的病机与治疗[J].辽宁中医药大学学报,2025, 27(10):94-97.
[23]韩冰莹,王萍,周水涵,等.基于伏瘀理论从免疫记忆探讨复发性银屑病病机与治疗[J].中国中西医结合杂志,2025, 45(4):475-481.
[24]王雨,钟祯,王晗,等.基于“伏邪理论”探讨带状疱疹各阶段病机特点[J].陕西中医药大学学报,2024,47(3):54-57.
[25]邹大涛.基于“伏邪”理论自拟“青蒿透邪饮”治疗玫瑰痤疮(肺胃热盛证)的临床疗效观察[D].成都:成都中医药大学,2020.
[26]张文娟,韩凌,危建安.从免疫性炎症疾病复发特征试论中医伏邪的生物学基础[J].中国中西医结合杂志,2023,43(2):236-240.
[27]陈家淇,郑秀丽.基于“伏邪温病”理论探讨EB病毒感染的中医病机与治疗思路[J].成都中医药大学学报,2024,47(4):42-45.
[28]QUE Z, QI D, YANG Y, et al. Regulating chemoresistance and cancer stemness:the CDH17-YAP pathway in distinct cellular states of lung cancer CTC clusters[J].Cell Mol Biol Lett, 2025,30(1):23.
[29]邓亮,刘建春,王青,等.从伏邪认识多发性硬化病因病机的探讨及启示[J].山西中医药大学学报,2023,24(7):761-764.
基本信息:
DOI:10.13288/j.11-2166/r.2025.24.002
中图分类号:R228
引用信息:
[1]王琦.伏邪理论的学术内涵及临床指导价值[J].中医杂志,2025,66(24):2517-2522.DOI:10.13288/j.11-2166/r.2025.24.002.