中医杂志

总结王宪波教授治疗乙型肝炎相关慢加急性肝衰竭（HBV-ACLF）的临证经验。认为HBV-ACLF属本虚标实之证，以脾虚为本，湿热毒瘀互结为标，提出“解毒凉血重通腑，健脾化湿顾中焦”的治疗观点。临证分型辨治HBV-ACLF，瘀热毒结证治以解毒凉血为法，常用解毒凉血方；湿热毒蕴证治以解毒凉血、健脾化湿为法，常用解毒凉血利湿方；脾虚湿热证治以健脾益气、清热化湿为法，常用解毒凉血健脾方（又称重肝2号方）。

By summarising Professor WANG Xianbo's clinical experience in treating hepatitis B virus associated acute-on-chronic liver failure(HBV-ACLF), it is believed that HBV-ACLF is a syndrome of root-cause deficiency and manifestation excess, with spleen deficiency as the root cause and dampness-heat-toxicity-blood stasis as the manifestation, and the therapeutic methods proposed as “detoxification and cooling of the blood to promote circulation of the internal organs, and strengthening spleen and resolving dampness to take care of the middle energizer”. In the treatment of HBV-ACLF, for syndrome of stasis-heat-toxicity mass, it was common to use the Jiedu Liangxue Formula(解毒凉血方) by detoxifying and cooling blood; For syndrome of dampness-heat-toxicity mass, it was common to use in the Jiedu Liangxue Lishi Formula(解毒凉血利湿方) by detoxifying and cooling the blood, strengthening the spleen and resolving dampness; For syndrome of spleen-deficiency and dampness-heat, it was common to use in the Jiedu Liangxue Jianpi Formula(解毒凉血健脾方, also known as Zhonggan No. 2 Formula) by strengthening the spleen and reple-nishing qi, clearing heat and resolving dampness.