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总结从“肝病三法”论治燥湿互结型干燥综合征的体会。提出燥湿互结型干燥综合征的主要病机为肝失疏泄致津停化燥,木土失和致内生燥湿,肝损及肾致燥极化湿。认为燥湿互结型干燥综合征有肝脾失调、体用失调的特点。根据《临证指南医案》中的“肝病三法”,认为当辛散理肝,破气机郁滞之结;甘缓和肝,断燥湿相兼之根;酸泻柔肝,润津液失调之困。三法协同,体用同治,燥湿自分,为燥湿互结型干燥综合征辨治提供新思路。
Abstract:This paper summarizes clinical insights on treating the syndrome of coexisting dryness and dampness in Sj?gren's syndrome(SS) based on the "three methods for liver diseases". It is proposed that the core pathogenesis of this subtype lies in the liver's failure to regulate and disperse, leading to fluid retention and transformation into dry-ness; disharmony between wood(liver) and earth(spleen), resulting in internal generation of dryness and damp-ness; and liver impairment affecting the kidney, eventually causing extreme dryness to transform into dampness. This syndrome is thus characterized by disharmony between the liver and spleen, as well as dysfunction between ti(character, 体) and yong(function, 用). Drawing from the Guide to Clinical Case (《临证指南医案》), the "three methods for liver diseases" are applied as follows,i. e. using pungent and dispersing herbs to regulate the liver and resolve qi stagna-tion; using sweet and gentle herbs to soothe the liver and address the root of concurrent dryness and dampness; and using sour and purgative herbs to soften the liver and restore fluid balance. The coordinated use of these three methods, treating both ti and yong, facilitates the separation of dryness and dampness, providing a novel approach to syndrome differentiation and treatment for this subtype of SS.
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基本信息:
DOI:10.13288/j.11-2166/r.2025.14.014
中图分类号:R259
引用信息:
[1]刘宇择,庞枫韬,何加乐,等.从“肝病三法”论治燥湿互结型干燥综合征[J].中医杂志,2025,66(14):1495-1498.DOI:10.13288/j.11-2166/r.2025.14.014.
基金信息:
中央高水平中医医院临床研究和成果转化能力提升项目(HLCMHPP2023002); 中国中医科学院中央级科研院所公益性基金(ZZ15-XY-PT-11);中国中医科学院科技创新工程(CI2021A01502)