中医杂志

胃癌术后化疗患者因手术直伤脾胃，化疗亦损正气，脾胃无力生荣，又有药毒内聚，荣气难抵骨髓，骨髓失其荣养难以化血，故致骨髓抑制。认为中焦枢机颓败、荣气周流失职、精髓失于荣养为病机核心，临证以升陷汤合当归补血汤为主补益中焦、提振中气，解决荣气不足之本；以复方丹参饮加减行气化瘀、解毒通络，解决荣气难抵骨髓之困；以大补元煎合二至丸加减方为基培本充髓，调养骨髓化生血液。

Patients with gastric cancer undergoing postoperative chemotherapy often develop myelosuppression due to direct injury to the spleen and stomach caused by surgery,depletion of healthy qi by chemotherapy,impaired generation of ying（荣） qi due to spleen and stomach deficiency,and the accumulation of drug toxicity,which prevents ying qi from reaching and nourishing the bone marrow.Consequently,the bone marrow loses its nourishment and becomes unable to generate blood,leading to myelosuppression.This paper proposes that the core pathogenesis involves failure of the middle jiao（焦） pivot function,dysfunction of ying qi circulation,and insufficient nourishment of essence and marrow.Accordingly,Shengxian Decoction（升陷汤） combined with Danggui Buxue Decoction（当归补血汤） is used as the principal prescription to tonify the middle jiao and uplift center qi,thereby remedying the fundamental insufficiency of ying qi.Modified Compound Danshen Decoction（复方丹参饮） is applied to promote qi circulation,resolve stasis,remove toxin,and unblock collaterals,thereby resolving the obstruction preventing ying qi from reaching the bone marrow.Modified Dabuyuan Decoction（大补元煎） combined with Erzhi Pill（二至丸） is taken as the foundational formula to cultivate the root,replenish marrow,thereby modulating hematopoiesis in bone marrow.